Gwendolyn Magee began quilting in 1989 and began considering herself an artist by 1995. Since then, her work has been featured in many books and publications. Her solo exhibit, "A Journey of the Spirit: The Art of Gwendolyn A. Magee" toured for two years to ten venues accompanied by a monograph of the same title.

Gwen's work is found in the permanent collections of the Smithsonian American Art Museum and the Mississippi Museum of Art and has been exhibited internationally. It is archived at the National Museum of Women in the Arts, and in 2006 she was named as an "Honored Artist" by its Mississippi State Committee. In 2005 she was awarded an Artist Fellowship Grant by the Mississippi Arts Commission and selected in 2004 to represent the state on, a showcase "…spotlighting the diversity and achievements of outstanding artists who live and work in the South." Gwen was recognized by the Mississippi Institute of Arts and Letters as Visual Artist of the Year in 2003.

Along with her husband, D. E. Magee, Jr., Gwen had two daughters, a son-in-law and two grandsons. Originally from High Point, North Carolina, she was a resident of Jackson, Mississippi from 1972 until her death in 2011.